SPRAVATO® Therapy at iMind
- SPRAVATO® (esketamine) is the first and only prescription nasal spray for depression
- FDA approved for Treatment Resistant Depression (TRD) and Major Depressive Disorder (MDD) with suicidal ideation
- iMind is proud to be a SPRAVATO® REMS treatment center
- We are the first in Port St. Lucie, Florida, to offer this breakthrough treatment
What is SPRAVATO® (esketamine)?
SPRAVATO® is a purified form of ketamine, treatments effect change within as soon as 24 hours whereas traditional anti-depressants can take 2-4 weeks to start working. SPRAVATO® is an NMDA receptor antagonist that is believed to work differently by acting on a pathway in the brain that affects Glutamate. SPRAVATO® uses your brains most powerful natural neurotransmitter (Glutamate) to boost the reduction in depression scores faster and safer.
- Provide relief of depression symptoms within as little as 24 hours
- Boost learning and memory, by clearing the depression “fog”
- Reduce brain activity associated with automatic negative thoughts (ruminations) when combined with psychotherapy
- Encourage the development of new connections in the brain when used with an approved anti-depressant
- Decrease suicidal thoughts when combined with psychotherapy
- Over time, retrain the brain to stay in this state with maintenance dosing and psychotherapy
SPRAVATO® is available only as a prescription nasal spray. Under the supervision of a certified healthcare provider, clients administer the medication themselves and are observed for a minimum of two hours to ensure there are no adverse effects.
Does SPRAVATO® Work?
In most clients, SPRAVATO® works in minutes to hours to significantly relieve symptoms. This is compelling, as antidepressants take six to 12 weeks to reach full effectiveness. Also, with antidepressants alone, up to half of people with depression fail to completely relieve their symptoms, while a third don’t receive any relief. SPRAVATO® can be a Godsend for these treatment resistant patients.
Justin Baksh, LMHC, BC-TMH, Chief Clinical Officer, iMind Mental Health Solutions
How does SPRAVATO® Work?
Provide fast-acting anti-depressant effects via a rapid surge of glutamate which activates postsynaptic AMPA receptors.
Increase brain plasticity, the ability of the brain to change and adapt by stimulating brain-derived neurotropic factor (BDNF) production and other means.
Decrease connectivity in areas responsible for endless negative thoughts, or rumination. These include connections between dorsal and pregenual anterior consulate cortex as well as the default mode network and prefrontal cortex’s executive control network.
Boost positive emotions and quell negative ones, by reducing overactivity in the lateral habenula, which affects the reward center. Overactivity here also leads to an inability to get the same enjoyment out of things previously enjoyed.
What is a SPRAVATO® REMS Treatment Center?
- Be REMS certified to receive, dispense, and treat patients with Spravato
- Ensure REMS patient enrollment with SPRAVATO® prescriber
- Directly observe and monitor patients being treated with Spravato for at least two hours
- Report to the SPRAVATO® manufacturer REMS program on a timely basis
iMind Mental Health Solutions is the first certified SPRAVATO® REMS treatment center in Port St. Lucie, Florida.
SPRAVATO®is making a real difference in the lives of people living with depression
Where do I begin. I have been to MANY places, had so many different doctors over the years. I was anxious waiting for my first Spravato appointment. But the moment you walk in the door, I was warmly greeted my Kim, who was warm and receptive. And my PA, Rachelle is angelic. I would recommend this place over any mental health provider from here to Miami. Im blessed to have found a compassion and beautiful establishment. I have nothing but relief and a great feeling of im in the right hands.
Shannon
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